Became a vegetarian after seeing The Texas Chain Saw Massacre (1974) but only for four years. Currently, he's no longer a vegetarian.
Turned down a chance to direct Blade: Trinity (2004), AVP: Alien vs. Predator (2004) and Harry Potter and the Prisoner of Azkaban (2004) to work on his dream project: Hellboy (2004).
Fought the film studios for almost seven years to get Ron Perlman for the title role in Hellboy (2004). The studio wanted a bigger name to ensure the success of the movie, but del Toro thought that Perlman was the perfect choice and wouldn't make the movie if he wasn't cast.
He is friends with fellow successful Mexican directors Alfonso Cuarón and Alejandro G. Iñárritu.
Has a photographic memory.
1997: His father was kidnapped in Mexico and held for seventy-two days until his ransom was paid.
In a January 2007 interview on the radio program "Fresh Air with Terry Gross," said that his strictly Catholic grandmother was a "Piper Laurie in Carrie (1976)" figure in his childhood. He told Gross that his grandmother would require him to mortify himself in self-punishment, in one case placing metal bottle caps into his shoes so that the soles of his feet were bloodied while walking to school. She also tried to exorcise him twice because of his persistent interest in fantasy and drawing monsters from his imagination.
His favorite movie monsters are Frankenstein's Monster and the Creature of the Black Lagoon.
In 2007, he was one of 10 Mexican Oscar-nominees. The others were Alejandro G. Iñárritu, Guillermo Arriaga, Adriana Barraza, Alfonso Cuarón, Guillermo Navarro, Emmanuel Lubezki, Eugenio Caballero, Pilar Revuelta and Fernando Cámara.
Lost 45 lbs. while making Pan's Labyrinth (2006), which he admitted in the DVD's video prologue.
Turned down a chance to direct I Am Legend (2007), One Missed Call (2008), Harry Potter and the Half-Blood Prince (2009) and Halo to work on Hellboy II: The Golden Army (2008).
Turned down the chance to direct Hellraiser: Bloodline (1996).
He regards Mimic (1997) as the weakest of his films and blames constant interference from the producers Bob Weinstein and Harvey Weinstein as the main reason, because they didn't respect his artistic vision. He later made peace with the film after creating a new Director's Cut.
Ranked #37 on EW's The 50 Smartest People in Hollywood. [December 2007]
Was asked to direct End of Days (1999), but he turned it down.
His movie and comic book collection is so huge that he had to buy an extra home to accommodate it.
Is good friends with director Robert Rodriguez.
Cites Bride of Frankenstein (1935) as his favorite movie.
His favorite albums are "The Wall" by Pink Floyd and "Security" by Peter Gabriel.
In an article in USA Today (August 22, 2011), del Toro listed his 6 favorite fright flicks: Freaks (1932), The Uninvited (1944), The Innocents (1961), Jaws (1975), Alien (1979), and The Shining (1980).
Children with Lorenza Newton: Mariana Del Toro and Marisa Del Toro.
Inducted into the Texas Film Hall of Fame during their gala held on March 12, 2015 in Austin, Texas.
Has extensive knowledge and practical experience playing video-games, and is very good friends with Japanese video-game designer/director Hideo Kojima, with whom he shares many interests, including 1960s classic movies and Japanese TV shows, and rare toys.
Used to work as an orderly at a mental institution and would eat lunch in a morgue next to it.
Was attached to direct The Hobbit: An Unexpected Journey (2012) but dropped out due to repeated delays in the production and the project stalling due to MGM declaring bankruptcy. He still received screenwriting credit on the film and its sequels: The Hobbit: The Desolation of Smaug (2013) and The Hobbit: The Battle of the Five Armies (2014).
His name translated into English is "William of the Bull".