Johnny Depp and Heather Graham in From Hell (2001)

Johnny Depp and Robbie Coltrane in From Hell (2001)

Directors Allen Hughes (left) and Albert Hughes (right) discuss a scene with Johnny Depp on a location in the Czech Republic.

Albert Hughes and Allen Hughes in From Hell (2001)

Adrien Brody at an event for From Hell (2001)

Anne Archer at an event for From Hell (2001)

Ashton Kutcher and Ashley Scott at an event for From Hell (2001)

Johnny Depp stars as Inspector Frederick Abberline

Mary Kelly (Heather Graham) is a woman living on the brink of society, earning a meager living with her body on the streets of the Whitechapel district of London.

Sgt. Godley (Robbie Coltrane) finds himself drawn deepen into the mystery surrounding the gruesome murders in the Whitechapel district of London.

The Ripper approaches his latest victim as she lays asleep in her bed.

Inspector Abberline (Johnny Depp), is the lone authority concerned with protecting the women being murdered on the streets of London by Jack the Ripper.

Inspector Abberline (Johnny Depp) is tormented by unendurable memories and seeks temporary escape with opium.  His addiction heightens spells of clairvoyance that lend insight to his investigation.

Inspector Abberline (Johnny Depp), promoted out of Whitechapel after years of service, finds himself assigned once again to the seedy district to lead the Ripper investigation.

Johnny Depp, Jason Flemyng, and Terence Harvey in From Hell (2001)