I have unfortunately never seen "Osmosis Jones", the movie which this series is based on, but I hear that this movie got a bad rap. If this is true, then Ozzy and Drix certainly redeems it's predecessor.
The plot involves the workings of the body of a teen named Hector. The "city" of Hector is depicted as a metropolitan city with all the cells and other fancy bits and bobs of the body working the boy that is Hector. Like any body, Hector is beset by diseases and symptoms. The show's main characters are the white blood cell, Osmosis "Ozzy" Jones, and his companion, the cold pill Drix. Just like a real cold pill, Drix is armed with a 120 nm (nanometer) smooth bore cannon for an arm ;) . These two heroes work a private eye gig of sorts, facing all the syndromes that Hector gets (and Hector seems to have "getting sick" as a part-time job).
As you've probably deduced by now, Ozzy & Drix is an educational cartoon. Those cartoons have always done VERY well in the past (I'm being sarcastic here, if you haven't witnessed the horror that is a educational cartoon before). Indeed, the first time you see Ozzy & Drix, you'd think it's an incredibly embarrassing series. But the cleverness of Ozzy & Drix is that while you learn about the human body and what can happen to it on the way, this educational stuff is not so at the forefront that you couldn't enjoy the cartoon as a hilarious and humorous parody of cop shows. For Ozzy and Drix excellently parodies the typical cop buddy movies and shows, Miami Vice coming off the top of my head. The city of Hector is like a city out of Grand Theft Auto, except without all the naughty content. All the cop show stereotypes, like the copper with street smarts, the bumbling mayor who needs serious help to keep his face good in the public, and the trench-coated informant in a shady alley are all included. The viruses and other germs are all typical "gangtas" and other criminals, with a few exceptions, shining out the most General Malaise and his (literal) army of bacteria with fake French accents.
All the while this is going on, it's all tied into typical ailments of the human body, which, as I mentioned, are not totally budging in front of the plot. Sure, the show teaches that ingestion of lots of sugar causes a rush of energy followed by tiredness, but it is depicted as a city-wide catastrophe of all cells growing lethargic and not doing their jobs, leaving the aforementioned French Napoleon-wannabe and his army to prepare for a body-wide assault. How do Ozzy & Drix thwart THIS menacing threat?! (that is a favorite episode of mine, by the way)
So seriously, if you thought of Ozzy & Drix to be another tiresome educational cartoon (the only good cartoon of this genre before was the infamous "Duck and Cover!" cartoon, teaching you that hiding under a table will save you from a close-range nuclear blast, and this was only funny because of it's unintentional absurdity), you are totally mistaken. While the life lessons are an integral part of the series, it is as much, if not more, a clever parody of the cop buddy genre, and other modern quirks. Watch at least a few episodes before your final verdict. ...unless, of course, you don't like cartoons in general, but then, why would you be reading these comments then?!
