The BAU is asked to investigate when 4 unconnected men go missing without trace. When the body of one victim is found the evidence just adds to the mystery.
The BAU heads south to investigate a fast-moving UnSub whose signature matches that of a serial killer from 30 years ago. Also, the team learns that someone is tracking their cases and replicating crimes the BAU has solved.
While Reid copes with a loss in his personal life, the rest of the BAU travels to San Francisco to investigate blood-drained victims discovered in the Mission District.
When the daughters of Bruce Morrison, a writer whose wife mysteriously vanished a year ago, go missing on the anniversary of their mother's disappearance, the BAU is brought in to study Morrison as a possible suspect.
When victims are found in Philadelphia in a similar style to victims of The Replicator, the stalker who has been tracking the BAU's every move, the team thinks this could be the break they need to try and apprehend him.
The BAU investigates victims who were documenting their personal lives and inner desires on blog posts and social media. Also, Kevin gets jealous when he learns Garcia may have a new love interest.
The BAU goes to Morgan's old neighbourhood in urban Chicago in search of an UnSub targeting middle-aged men, and a clue leads Morgan to believe that they are after someone connected to the man who molested him as a child.
When a time capsule in a small Colorado town is opened 25 years later and contains a gruesome discovery, the BAU investigates that crime and a possible link to the death of a local police officer.
The BAU travel to Rapid City after two male victims are discovered murdered in a ritualistic manner. Also, Reid continues to grieve over Maeve's death.
As The Replicator hones in on one of the BAU, Hotch gets a call from his estranged brother when party people in New York begin "boiling" from the inside out.