Conan O'Brien was born in the same neighborhood as JFK, went to the same university, and like Kennedy is also an Irish-Catholic.
The narrator, Peter Coyote, was invited into the Kennedy White House in 1962, after demonstrating in an anti-war protest during the Cuban Missile Crisis
The series was filmed in more than 25 states, including interviews and new b-roll footage in locations like Hyannis Port, Boston, and Washington D.C.
On a few occasions throughout the series, actor Bruce Greenwood voices John F. Kennedy. Greenwood played Kennedy in the film Thirteen Days (2000) alongside Academy Award-winning actor Kevin Costner.