At the end of the film when K leans back against the steps, you can see an indention in the snow where his elbow had already been placed, indicating this shot was the second take.
When K meets the 3 hookers, there are lots of foreign language ads all around, one of them is for Coca Cola but in Hebrew. The letters flash on and off and then light each letter individually. The order in which they light up is left to right, and not as it should be, since it's Hebrew, right to left.
When Deckard is struggling to free himself as the hovercar fills with water, his hair alternates between dry and wet, even after he puts his head underwater.
The back of K's jacket gets dirty during the fight before reaching the orphanage and then is completely clean when inside the orphanage.
When Sapper Morton is in the pool checking on his grubs, it doesn't look like they could swim, so they'd all be on the bottom of the pool and he would be crushing them under his boots as he walked. It would be easy enough for the pool to have a metal grid, supported a few inches off the bottom ; on which he could walk., but reach through for the grubs.
The Memory Bearings are optical devices, so how were they affected by the Blackout of 2022, which was caused by an electro-magnetic pulse ? The memory bearings are read optically, but we can only guess how they are written, and edited ; a punched card is also read optically, but it would be "edited" by a shotgun, and "erased" by a rainstorm.
The first song listed ("Summer Wind"), is displayed as "Perfromed by Frank Sinatra" instead of "Performed by Frank Sinatra".
The tritium radiation of the wooden horse figurine (the Trojan Horse) leads blade runner KD6-3.7 (Joe) directly to where Deckard has been hiding, but Deckard has been on the run and was already in hiding long before the birth event on 10th June 2021. So exactly how did the child being chased when at the orphanage, get the wooden horse figurine, and subsequently hide it? Either someone else transported the wooden horse figurine from Deckard to the orphanage, or perhaps Deckard left the wooden horse figurine with pregnant Rachael (N6FAA52318) as a unique gift for their child, or there is a large plot hole here.
It was Freysa, leader of the rebel Replicants, who (with Sapper) hid Ana Stelline after she was born. This must mean that Freysa had Deckard's complete trust, and it was she who transported the horse from him to his daughter after the radiation event but before young Ana hid the figurine.
We see a number of bee hives and agent K's hand covered with bees. However the area is devastated, there is no sign of life and certainly no flowers from which the bees can harvest nectar. But then we do not know if these are synthetic or in fact if they are honey producing bees.
During the test clip shown of Rachel, supposedly some of the only data on her had by Wallace, we are clearly shown that her eyes are green. Yet when they attempt to tempt Deckard by an exact copy of her, they seem to fudge up this detail. This is a mistake by, or a technical shortcoming of, the Wallace Corporation ; which was noticed by Deckard. It isn't a plot-hole goof by the film-makers.
While exploring the abandoned casino, K gives a casual one-handed spin to a roulette wheel. The soundtrack adds the rattling noise of a roulette ball (or pill) landing in a pocket, even though K clearly does not pick up a ball or launch one.
Only about two-thirds of the wheel is seen before K spins it, so the ball could have been sitting in the non-visible third ; and the camera quickly cuts away, so it could not be seen flung out and spinning.
However, this cannot be so since a roulette wheel is designed such that a ball does not simply sit there, but will naturally roll into a number pocket, even if the wheel is stationary. And if the wheel is then casually spun, the ball is not flung out but will remain trapped in its pocket. This behavior of the ball is required to show that the wheel is not rigged.
And furthermore, the Accidentally Flung Ball scenario is not seen to happen in the "Time to Live" featurette, which has a longer shot of this scene where the camera doesn't cut away.
When Luv takes K to the room where the data files are stored, the heavy door jams about half way when opening. She then uses physical strength to open it with her hands (with no apparent effort), but she is wearing elegant shoes with heels on a slippery floor. It would be physically impossible for her to apply enough force on the heavy door to open it without having a good grip on the ground, regardless of her superhuman strength. She would normally slide away when trying. This being 2049, with advances in technology prompted by decades of litigation and compensation ; we can safely presume that such shoes have a means to "grip" at least artificial floors. That would be a trivial technical problem, compared to other portrayed technology : hover-cars, holograms that can see, instant showers, off-world travel, replicants etc. etc.
In Sapper Morton's kitchen, in the wide shots at the start of the scene, the flame under the pot is on full . Later, when the pot is in the foreground, the flame is much lower. At the end of the scene, as K opens the lid and smells the garlic, the flame is medium-high.
When Agent K arrives where Deckard has been living all those years,a bee flies on his hand. When the bee flies away, the sound we hear is of a fly not a bee. But then we do not know if these are synthetic, or what type of bee they are supposed to be.