Oscar Issac and Sonoya Mizuno previously starred together in Ex Machina, written and directed by Alex Garland.
This will be the second collaboration between Alex Garland and Oscar Isaac after Ex Machina (2014).
Natalie Portman, Tessa Thompson, Oscar Issac, Benedict Wong, David Gyasi and Alex Garland have worked on at least one comic book movie: . Portman starred in both Thor (2011), Thor: The Dark World (2013), and V for Vendetta (2005) . Thompson starred in Thor: Ragnarok (2017) and Avengers: Infinity War (2018) . Issac starred in X-Men: Apocalypse (2016) . Wong starred in Kick-Ass 2 (2013) and Doctor Strange (2016) . Garland wrote the script for Dredd (2012) . Gyasi starred in The Dark Knight Rises (2012)