This movie is based on how Kumail Nanjiani, and his real life wife (co-writer) Emily V. Gordon, met and fell in love.
The film premiered at the Sundance Film Festival where it was highly well received. Which started a bidding war for the distribution rights between Sony, Focus Features, Amazon, & Netflix. Co-creator of the film, Kumail Nanjiani wanted the film to have theatrical distribution which eliminated Netflix from the bidding war because they're not a proponent in that distribution model. The film's distribution rights were eventually bought for around $12 million by Amazon who is a big proponent of the theatrical experience, with all of its films getting at least some kind of theatrical run. The $12 million dollar deal is one of the largest deals in Sundance's history.
Kumail Nanjiani and Emily V. Gordon had a podcast called The Indoor Kids where they discussed video games. The name refers to a line from Wet Hot American Summer which director Michal Showalter co-wrote.
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