The production was delayed by some setbacks when director Matt Spicer accidentally walked through a sliding glass door after yelling "cut" and gaffers had to remove fragments of glass from his arm with duct tape. At one point the production had to evacuate their location due to the raging Santa Clarita brush fires in L.A. county.

This will be O'Shea Jackson Jr. 's second movie ever; his first was playing his father in Straight Outta Compton (2015).

Elizabeth Olsen, Pom Klementieff, and Aubrey Plaza have all previously been in either a Marvel movie, or TV series. Elizabeth in Captain America: The Winter Soldier (2014), Avengers: Age of Ultron (2015) and Captain America: Civil War (2016), Pom in Guardians of the Galaxy Vol. 2 (2017), and both in upcoming Avengers: Infinity War (2018). Aubrey appears as the antagonist in Fox's Legion (2017).

The short film "Hi Stranger (2016)" was attached to this film in the United States/Canada by distributor Neon.

Pom Klementieff and Elizabeth Olsen have worked together in Old Boy (2013) and will work together again for Avengers: Infinity War (2018).

Pappy and Harriet's, the bar that the characters visit while staying in Joshua Tree, was a principal location for THE HOWLING: NEW MOON RISING (1995).

Like his character in the film, Wyatt Russell does not participate in social media at all. This is ironic, considering the theme of the film.