Sebastian Castellanos (voice)
Juli Kidman (voice)
Lily Castellanos (voice) (as Kiara Gamboa)
Myra Castellanos (voice)
The Administrator / Union Citizen 2 (voice)
Stefano Valentini (voice)
Theodore Wallace (voice)
Tatiana Gutierrez / Woman on Train (voice)
Liam O'Neal / Harbinger (voice)
Yukiko Hoffman (voice) (as Ying Hsiao)
Julian Sykes / Mobius Operative 4 (voice)
Esmeralda Torres (voice)
Ryan Turner / Mobius Operative 1 (voice)
James Hayes / Union Citizen 1 (voice)
Miles Harrison (voice) (as Christopher Kohls)
Obscura / Guardian 1 / Anima (Ghost) / Hysteric / Female Lost 2 / Security Door (voice) (as Christina Calph)
Torture Victim / Mobius Operative 2 (voice)
Psychiatrist / Male Lost 1 (voice)
Male Lost 2 (voice)
Laura / Feeder Woman / Mobius Researcher (voice)
Harbinger (Zealot) / Mobius Security 1 (voice)
Woman (voice)
Priest / Harbinger (Black Knight) / Security Announcement / Security Door (voice)
Anima (Ghost) / Guardian 2 / Female Lost 1 (voice) (as Nathalie Soderqvist)
Mobius Operative 5 (voice)
Sadist (voice) (as Ippei)
Additional Creature Voices (voice)
Black Cat (voice)
Sebastian Castellanos / Lost / Mobius Operative
Stefano Valentini / Theodore Wallace / Harbringer / Lost
Sebastian Castellanos
Myra, Yukiko Hoffman
Myra Castellanos (emotion facial capture)