Nick Birch / Maury the Hormone Monster / Coach Steve Steve / Lola Skumpy / Judge Joe Brown (voice)
Andrew Glouberman (voice)
Jessi Glaser (voice)
Jay Bilzerian (voice)
Missy Foreman-Greenwald (voice)
Elliot Birch (voice)
Diane Birch / Connie the Hormone Monstress / Ghost of Whitney Houston (voice)
Ghost of Duke Ellington / Ghost of Freddie Mercury / Ghost of Prince (voice)
(voice)
Lars (voice)
Edward MacDell (voice)
Judd Birch (voice)
Leah Birch (voice)
Marty Glouberman (voice)
Jenna Bilzerian (voice)
Cellsea (voice)
Aiden (voice)
Matthew MacDell (voice)
Ghost of David Bowie (voice)
Gordie (voice)
Kimberly MacDell (voice)
Ghost of Freddie Mercury (singing voice) (uncredited)