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- An NFL quarterback living the bachelor lifestyle discovers that he has an 8-year-old daughter from a previous relationship.
- A teenager is bullied by her former friends when they discover that she has a crush on the same boy as the most popular girl in school does.
- A government scientist and his tough, attractive FBI handler try to save people from deadly scientific experiments, poisoners, rare diseases, and environmental hazards.
- Based on a memoir by Sue William Silverman about her struggle and triumph over sexual addiction.
- Starring Natasha Henstridge and James Brolin. A wealthy man marries a sexy young hospice nurse. When he dies suspiciously and the new missus inherits a fortune, his daughter grows convinced that her gold-digging stepmother is to blame.
- Holly Winters (Tori Spelling) is an unhappy-in-love, prosecuting attorney. After suffering a serious head injury, she gains the psychic power to read minds and decides to use this new-found power to catch a killer...
- A troubled teen goes to live with her dad in a small town to reflect on her questionable choices. Unfortunately, she clashes with her father's new wife, who is pregnant.
- A Global Health Organization physician investigating a sudden outbreak in Spokane, WA, grows more and more determined the outbreak is connected to a clandestine military operation.
- Miranda Wells is a charismatic attorney dealing with for illegal immigration and murder, taking on a case for her acquaintance Miranda - being under suspicion of killing her husband.
- Ten celebrities are abandoned in the Australian outback with only minimal means of survival, in order to raise money for charity.
- Pediatrician by day, single mom by night, Sarah invites her estranged husband, Pete, back to their suburban home for the Holidays on one condition: he must reconcile with their daughters before she agrees to finalize a trial separation with divorce.
- Dr. Maddy Rierdon, an investigator for the Department of Agriculture, is the only person who can protect America from a deadly breed of bioengineered locusts.
- Prudence McCoy is the host of a successful helpful hints TV show, who discovers a hidden talent for crime solving.
- A woman witnesses the murder of a prosecutor by a criminal he is trying to convict. She informs the FBI, who then places her and her family in Witness Protection. And their lives are turned upside down. The agent tries to get the criminal but it seems he has someone in the FBI helping him. And when her daughter calls her boyfriend, it places her family in danger.
- Waitress Elise's dream to become a painter isn't going anywhere, unlike her ex Gerry's, so she eagerly accepts to house-sit a month the country estate eccentric gentleman Frank inherited with a fabulous coin collection while he is in Boston for business. A leaky pipe makes her call a plumber not from Frank's 'call only' list, and Phil soon ends up sharing the bed with her. When Frank returns early, with grand plans beyond her wildest dreams, the stage is set for tragedy.
- A white woman has an affair with a married African-American basketball star and challenges him for custody of their mixed-race son. Based on a true story.
- When Isabel Darden, a successful, attractive 30-year-old woman, grows tired of people asking her "when are you going to get married," she decides to honor the person she loves the most, by tying the knot with herself.
- A woman returns to her childhood town after splitting from her husband. The town is gripped by a spree of burglaries. As she left under a cloud the town's gossipers think she might be involved.
- Die-hard gamers tough it out in a series of contests to decide who is the ultimate gamer
- Former NYPD detective Joe Mazzilli leads a team of private investigators -- real-life superheroes, some call them -- who track runaways with the hope of reuniting them with their families.
- Ally is an irrepressible romantic, but when she gets cold feet on the eve of her engagement she is visited by three "spirits" of boyfriends Past, Present, and Future.
- A scientist researches the genetic cause of addictive behavior.
- In Memphis, Sgt. Terry Max takes on the murder case of a 78-year-old man shot outside his home. The outraged community quickly helps apprehends the two young suspects, but getting them to talk proves more difficult. In Dallas, Det. Bob Ermatinger investigates the difficult case of a woman found shot to death while collecting wildflowers. Each new lead just deepens the mystery.
- When evidence suggests that someone is attempting human cloning, Dr. Jacob Hood, Special Science Advisor to the FBI, is called in to investigate.
- Water purported to cure cancer puts Hood and Rachel searching for a scientific explanation, but the answer is more deadly than the diseases it's supposed to be curing.
- The autopsy of a middle-aged but youthful-looking man reveals that he had a second heart.
- Hood is called in when autistic children begin to be abducted, only to reappear apparently on the road to recovery. But when one dies, solving the mystery of where the children go lies in the head of one of the abductees, and she may be the only lead to saving the latest kidnapped child.
- Genetic Modified (GM) food results in poisoning of several people.
- Hood consults when a virus attacks a city worker, and its source may be closer to home than anyone expects.
- The appearance of frozen bodies on sunny California days puts Hood on the trail of a chemical compound, and a madman determined to stop what he sees as a perversion.
- Hood is called in to clean up a mess at a secret government project, but when it turns out the study subjects are not what they're supposed to be, the race is on to prevent any more deaths.
- When students at a land-locked university begin dying of the bends, Hood must not only crack the science but devise a cure.
- When some young men appear to die. They later come back to life. Hood and Young investigate and suspect they're dealing with a bacteria.
- Children in a small Georgia town are mysteriously dying...from heart attacks.
- Gepetto resurfaces with the discovery of identical quadruplets from different mothers, leaving Hood and Rachel scrambling for clues to identify her, and the hit man she's hired, before another murder occurs.
- Dr. Jacob investigates an epidemic of violent outbursts by usually law-abiding citizens in a small Texas community but then exhibits to the same erratic behavior.
- Hood, along with agents Young and Lee, tries to locate the cause of an outsize number of electrocution injuries and deaths before another storm hits.
- A case of mercury poisoning that could turn into an epidemic puts Hood, Young and an eager field agent to work tracing the source of the mercury, but as every lead becomes a dead end they must begin looking for an unnatural cause.
- New York's fashion week turns deadly, and it's up to Hood to figure out how one sniff of a perfume causes the violence.
- Hood is called in when people in Philadelphia begin falling victim to an unknown poison that affects the nervous system and causes one to become a fireball.
- The contestants are broken into teams to perform The Donnas' "New Kid in School" live at The Music Box Theater. Isolation Challenge: the contestants performed Lit's "My Own Worst Enemy" on Rock Band 2.
- The contestants complete a combat course in which teams must break boards throughout the maze to score. Elimination Challenge: Two contestants played head-to-head to survive.
- In Memphis, Sgt. Bart Ragland must find out who shot and robbed a family man. In Tucson, Detective Jim Hanson hunts two suspects who allegedly gunned down a local high school student as he and his friends walked home from the mall.
- Hood goes up against an FBI deputy director when a psychotic woman accuses the man of stealing her son, and the stakes go much higher when Rachel is taken hostage and Jacob is accused of complicity in the crime.
- Tayvela felt "trapped" in her Long Island home by her over-protective, but well-meaning, mother.