Alex Thompson and Kelly O’Sullivan, the filmmaking duo behind the acclaimed Sundance film “Ghostlight,” have wrapped production on their follow-up feature, “Mouse.” It’s the story of best friends Minnie (Katherine Mallen Kupferer) and Callie (Chloe Coleman), whose relationship is upended on the eve of their senior year.

Written by O’Sullivan and co-directed by O’Sullivan and Thompson, the film is set and was shot on location in North Little Rock, Ark., which also happens to be O’Sullivan’s hometown. “Mouse” stars Sophie Okonedo, Katherine Mallen Kupferer, Chloe Coleman and Tara Mallen. The ensemble includes Iman Vellani and David Hyde Pierce. The film also features newcomers Beck Nolan, Addisyn Cain, Audrey Grace Marshall and Christopher R. Ellis.

Okonedo is a Tony winner, as well as an Emmy and Oscar nominee, whose credits include “Slow Horses” and “Hotel Rwanda.” Kupferer starred in “Ghostlight” and “Are You There God? It’s Me Margaret.