It's not unusual to see network shows bring back fan-favorite characters, no matter how long they've been absent from the show, more so for Grey's Anatomy. Grey Sloan Memorial frequently shuffles between old and new characters, a recent example being the return of Dr. Sydney Heron 17 years after her last appearance with actress Kali Rocha returning to reprise the role. While Rocha's return was divisive among the fandom, one character that would almost unanimously excite fans if they were to come back is Dr Alex Karev, played by Justin Chambers. Chambers is one of the show's original cast members who spent 15 years playing the fan-favorite character before his heartbreaking departure in 2020.