When Max Mutchnick and David Kohan first partnered on “Will & Grace,” they paved the way with a fresh sitcom that was immediately embraced by queer communities. Now, over two decades later, the duo hopes to reinvent the genre once again with Hulu’s “Mid-Century Modern.”

“I hope we’re able to be a show that breaks the mold of a multicam a little bit in the way that we get to sound a little bit more like the world sounds,” Mutchnick told TheWrap. “The gift of working at Hulu is that we got a chance to graduate to a language and a sound and a cadence that really is more like what we sound like. I hope that that’s one of the things that’s able to stick with this show, which is, it’s a little bit more grown up.”

“Mid-Century Modern” centers on three gay best...