Alyssa Milano in Project Runway Junior (2015)

Alyssa Milano, Debra Messing, Isaac Mizrahi, Georgina Chapman, and Anne Fulenwider in Project Runway All Stars (2012)

Alyssa Milano in Project Runway All Stars (2012)

Alyssa Milano, Isaac Mizrahi, Georgina Chapman, and Nina Garcia in Project Runway All Stars (2012)

Alyssa Milano, Boy George, Isaac Mizrahi, and Georgina Chapman in Project Runway All Stars (2012)

Alyssa Milano, Debi Mazar, Isaac Mizrahi, Georgina Chapman, and Zac Posen in Project Runway All Stars (2012)

Alyssa Milano and Yvonne Niami in Project Runway All Stars (2012)

Alyssa Milano, Isaac Mizrahi, Georgina Chapman, and Kristin Cavallari in Project Runway All Stars (2012)

Alyssa Milano, Isaac Mizrahi, Georgina Chapman, Brad Goreski, and Kesha in Project Runway All Stars (2012)

Alyssa Milano and Laura Michelle Kelly in Project Runway All Stars (2012)

Alyssa Milano, Isaac Mizrahi, Georgina Chapman, and Megan Hilty in Project Runway All Stars (2012)

Alyssa Milano, Tony Danza, Katherine Helmond, and Judith Light in Television (1988)

Alyssa Milano and Arnold Schwarzenegger in Commando (1985)

Alyssa Milano in All the World's a Runway (2019)

Alyssa Milano, Isaac Mizrahi, Georgina Chapman, and Andrea Riseborough in All the World's a Runway (2019)

Alyssa Milano, Isaac Mizrahi, Andrea Riseborough, Irina Shabayeva, Dmitry Sholokhov, Michelle Lesniak, and Anne Fulenwider in All the World's a Runway (2019)

Alyssa Milano, Isaac Mizrahi, Georgina Chapman, Andrea Riseborough, Evan Biddell, Irina Shabayeva, Dmitry Sholokhov, Michelle Lesniak, and Anne Fulenwider in All the World's a Runway (2019)

Alyssa Milano, Isaac Mizrahi, Georgina Chapman, Andrea Riseborough, and Irina Shabayeva in All the World's a Runway (2019)

Alyssa Milano, Georgina Chapman, and Dmitry Sholokhov in All the World's a Runway (2019)

Alyssa Milano, Isaac Mizrahi, Georgina Chapman, Nina Garcia, and Iris Apfel in Nina Says Don't Cry Over Spilt Silk (2019)

Alyssa Milano in Nina Says Don't Cry Over Spilt Silk (2019)

Alyssa Milano in Climate Quick Change (2019)

Alyssa Milano, Isaac Mizrahi, Georgina Chapman, Reem Acra, and Cynthia Erivo in Climate Quick Change (2019)

Alyssa Milano, Isaac Mizrahi, Georgina Chapman, and Asia Kate Dillon in Project Runway All Stars (2012)

Alyssa Milano, Rose McGowan, and Holly Marie Combs in Charmed (1998)

Alyssa Milano, Rose McGowan, Holly Marie Combs, and Shannen Doherty in Charmed (1998)

Drew Barrymore, Alyssa Milano, Tom Skerritt, Belinda Bauer, Cheryl Ladd, Camilla Belle, Sara Gilbert, Jaime Pressly, Xander Berkeley, Megan Edwards, and Greg Vaughan in Poison Ivy (1992)