Mary-Louise Parker and Cicely Tyson in Fried Green Tomatoes (1991)

Mary Stuart Masterson and Mary-Louise Parker in Fried Green Tomatoes (1991)

Mary Stuart Masterson, Mary-Louise Parker, Kathy Bates, Jessica Tandy, Cicely Tyson, and Fannie Flagg in Fried Green Tomatoes (1991)

Mary-Louise Parker in Fried Green Tomatoes (1991)

Mary-Louise Parker and Demián Bichir in Weeds (2005)

Mary-Louise Parker and Guillermo Diaz in Weeds (2005)

Mary-Louise Parker, Demián Bichir, and Hemky Madera in Weeds (2005)

Mary-Louise Parker and Justin Kirk in Weeds (2005)

Mary-Louise Parker, Justin Kirk, and Demián Bichir in Weeds (2005)

Mary-Louise Parker and Alexander Gould in Weeds (2005)

Mary-Louise Parker and Elizabeth Perkins in Weeds (2005)

Jennifer Jason Leigh and Mary-Louise Parker in Weeds (2005)

Mary-Louise Parker in A Place for Annie (1994)

Mary-Louise Parker and Sissy Spacek in A Place for Annie (1994)

Mary-Louise Parker, Sissy Spacek, Jack Noseworthy, and Joan Plowright in A Place for Annie (1994)

Mary-Louise Parker and Lily Rabe in Golden Exits (2017)

Mary-Louise Parker in Golden Exits (2017)

Mary-Louise Parker and Chloë Sevigny in Golden Exits (2017)

Mary-Louise Parker and Sidney Poitier in The Simple Life of Noah Dearborn (1999)

Mary-Louise Parker in The West Wing (1999)

Mary-Louise Parker and Meryl Streep in Angels in America (2003)

Mary-Louise Parker and Paul Giamatti in Billions (2016)

Mary-Louise Parker and Eric Stoltz in Naked in New York (1993)

Mary Stuart Masterson, Mary-Louise Parker, Kathy Bates, and Jessica Tandy in Fried Green Tomatoes (1991)

Drew Barrymore, Whoopi Goldberg, and Mary-Louise Parker in Boys on the Side (1995)

Henry Fonda, Katharine Hepburn, Jane Fonda, Mary Stuart Masterson, Mary-Louise Parker, Meryl Streep, Kathy Bates, and Jessica Tandy in On Golden Pond (1981)

Mary-Louise Parker and Michael Silverman in The Best Thief in the World (2004)

Mary-Louise Parker and John Turturro in Sugartime (1995)

Elias Koteas, Mary-Louise Parker, John Turturro, and Maury Chaykin in Sugartime (1995)