His first child with his wife Sarah Trigger, a son Charlie Austin, was born on 27 June 2000 in Los Angeles.
Attended and graduate of The Bronx High School of Science (aka Bronx Science) in 1983.
Son of David Cryer and Gretchen Cryer, Broadway actors.
He was asked to audition for the role of Chandler Bing on Friends (1994), while he was doing a play in London. His reading was videotaped by a British casting agent but the tape failed to arrive in the United States before the network had made its final decision.
Friends with Paget Brewster.
He and his Two and a Half Men (2003) co-star Charlie Sheen also starred together in Hot Shots! (1991)
(January 23, 2007) Revealed his engagement to television reporter Lisa Joyner on The Tonight Show with Jay Leno (1992).
Has one sister: Robin Cryer.
Attended Stagedoor Manor Theatre Camp.
Once an usher at the Equity Library Theater, where he was often mistaken for actor Matthew Broderick.
Assumed temporary custody of his son, Charlie, after Charlie's mother, Sarah Trigger, was arrested in May 2009 on felony neglect charges. Charlie's two-year-old stepbrother was found with rope and cord marks around his neck.
Daughter, Daisy, born 11 August 2009; adopted by Jon and Lisa shortly after.
Attended Junior High School 104 in New York City, with fellow actors Robert Downey Jr., Erica Gimpel and Kadeem Hardison.
Received death threats via telephone while shooting Two and a Half Men (2003). [January 2010]
Received a star on the Hollywood Walk of Fame at 6922 Hollywood Boulevard in Hollywood, California on September 19, 2011.
Cryer's two front teeth are fake after having lost his two front teeth while diving into the shallow end of a swimming pool.
Attended Junior High School 104 with Robert Downey Jr. He co-starred with him in the comedy film Due Date (2010).
He is of Dutch, English, German, Swiss-German, Scottish, and Swedish ancestry.
Appeared, with Charlie Sheen, in a PSA for the "Wounded Warriors Project" (2009).
Was considered for the role of Chandler Bing on Friends (1994) .
In the 1986 movie "Pretty in Pink," Cryer played his first notable role, a character called "Ducky". In 2015-16, he played a recurring character on NCIS called Dr. Cyril Taft, opposite David McCallum's character, Dr. Donald "Ducky" Mallard. At one point in the 2016 episode "Loose Cannons," Cryer, as Taft, says "That would be just ducky, Ducky. I've been dying to say that!".
Born on the exact same day as Martin Lawrence.
He is the first actor to play Superman's arch-enemy Lex Luthor who was bald before being cast and didn't need to shave their head for the role.