Graduated from the William Esper Studio.
She worked as a hat-check girl at a restaurant where her agent-to-be spotted her and got her a Coca-Cola commercial.
Her mother is an artist and her father is a special ed teacher at RHAM High School. Her parents divorced when she was young. She has an older brother, Jim Mol.
Graduated from the prestigious American Musical and Dramatic Academy. That is the same school that actors such as Lee Tergesen (Oz (1997)), Tyne Daly (Judging Amy (1999)) and Paul Sorvino (Goodfellas (1990)) attended.
Went to the same high school as Broadway actor Peter Lockyer.
Grew up in Connecticut. Moved to New York as a teenager to study acting.
Worked with her husband's ex-wife (Famke Janssen) on three films - two before she married him (Rounders (1998) and Celebrity (1998)) and one after she married him (The Ten (2007)).
Son Ptolemy John Williams, born 10 October 2007.
Is expecting her second child with husband Tod Williams.
Second son, Winter Morgan Williams, was born on February 17, 2011 in New York.
In addition to being an American Musical and Dramatic Academy alumni with Lee Tergesen, Gretchen also graduated from the same high school(Valley Regional High School in Deep River, Connecticut) as Lee Tergesen. Other notable Valley grads include Justin Haut and Peter Lockyer.
She is of Dutch (from her paternal grandfather), English, French, Welsh, and Irish ancestry. She is a direct descendant on her mother's side (Morgan) of William Brewster, leading elder of the Pilgrims of the Mayflower, and Cornwall-born Capt. James Avery, Commander of the Pequot Indians. Gretchen's family arrived on the Mayflower and settled in the Stonington, CT, area shortly thereafter.
Was on the cover of the September 1998 issue of Vanity Fair magazine described as "Hollywood's next It Girl".
A character in the film Mary (2005) was named after her. Mol worked with the film's director, Abel Ferrara, in three films: The Funeral (1996), SUBWAYStories: Tales from the Underground (1997), and New Rose Hotel (1998).