Mandy Patinkin in The Princess Bride (1987)

Mandy Patinkin and Olivia Cooke in Life Itself (2018)

Mandy Patinkin, Lucy Liu, and Shawn Mendes in The Late Late Show with James Corden (2015)

Mandy Patinkin and Stephen Colbert in The Late Show with Stephen Colbert (2015)

Claire Danes and Mandy Patinkin in Homeland (2011)

Mandy Patinkin and Jacob Tremblay in Wonder (2017)

Cary Elwes, André René Roussimoff, and Mandy Patinkin in The Princess Bride (1987)

Mandy Patinkin and Stéphanie Guerin in Homeland (2011)

Mandy Patinkin and Natacha Karam in Homeland (2011)

Mandy Patinkin and Alfredo Narciso in Homeland (2011)

Mandy Patinkin and Shemar Moore in Criminal Minds (2005)

Mandy Patinkin and Adam Arkin in Chicago Hope (1994)

Barbra Streisand and Mandy Patinkin in Yentl (1983)

Hector Elizondo, Mandy Patinkin, Adam Arkin, Roxanne Hart, and E.G. Marshall in Chicago Hope (1994)

Barbra Streisand, Amy Irving, and Mandy Patinkin in Yentl (1983)

Hector Elizondo, Mandy Patinkin, Adam Arkin, and E.G. Marshall in Chicago Hope (1994)

Hugh Grant, Judy Davis, Mandy Patinkin, Bernadette Peters, Julian Sands, and Michael Ochs in Impromptu (1991)

Mandy Patinkin, Thomas Gibson, and Shemar Moore in Criminal Minds (2005)

Mandy Patinkin and Vanessa Williams in The Adventures of Elmo in Grouchland (1999)

Elizabeth McGovern and Mandy Patinkin in Broken Glass (1996)

Salma Hayek and Mandy Patinkin in The Hunchback of Notre Dame (1997)

Salma Hayek, Richard Harris, and Mandy Patinkin in The Hunchback of Notre Dame (1997)

Antonio Banderas, Cary Elwes, Robin Wright, André René Roussimoff, Mandy Patinkin, and Heath Ledger in The Princess Bride (1987)

Mandy Patinkin, Jasmine Guy, Callum Blue, Laura Harris, and Ellen Muth in Dead Like Me (2003)

James Caan and Mandy Patinkin in Alien Nation (1988)