Played linebacker in High School.
His family moved to Omaha, Nebraska, USA at age 11.
Was discovered in his high school by director Alexander Payne who was scouting locations for Election (1999).
Played Tony in his high school production of West Side Story.
Is a member of Lambda Chi Alpha fraternity.
He was the only one of the five original boys from the series to not appear in American Wedding (2003). When queried, writer Adam Herz stated that they did not have enough for Chris to do, and that it was hard enough to fit the currently existing cast in. They were unable to do a cameo appearance because Chris was in London during filming, and the budget would not allow for the expenses of having him flown in for just a few scenes.
Engagement to actress Katie Holmes called off in March 2005.
Has an older sister and a younger brother.
His mother is a teacher in Orange County, California
Attended Texas Christian University in Fort Worth, Texas, where he was a member of Lambda Chi Alpha.
Was in a relationship with Ginnifer Goodwin for two years, until December 2008.
Filming American Dreamz (2006). [September 2005]
Lending his voice to The Wild Bunch. [October 2009]
His father is of 3/4 German and 1/4 Irish descent. His mother is of Irish, as well as German and English, ancestry.
Became a father for the 1st time at age 37 when his wife Laina-Rose Thyfault gave birth to their son Frederick Easton Klein on July 23, 2016.
His first name and his son's name Frederick is a Germanic name meaning "peaceful ruler".
His surname Klein means "little" in German.
His second name Christophe is a Greek name meaning "a bearer of Christ".
Married Laina Rose Thyfault in Big Sky, MT along the Gallatin River in a beautiful outdoor wedding ceremony during the summer of 2015.