Kelly Rutherford and Thomas Calabro in Melrose Place (1992)

Kelly Rutherford, Christopher Gorham, Mario Lopez, and Rainn Wilson in The Stream (2013)

Kelly Rutherford and Matthew Settle in Gossip Girl (2007)

Heather Locklear, Rob Estes, Jamie Luner, Kelly Rutherford, Josie Bissett, Thomas Calabro, John Newton, and Jack Wagner in Melrose Place (1992)

Wallace Shawn, Desmond Harrington, Kelly Rutherford, Michelle Trachtenberg, Penn Badgley, Margaret Colin, Blake Lively, Leighton Meester, Chace Crawford, Ed Westwick, and Zuzanna Szadkowski in Gossip Girl (2007)

Wallace Shawn, Desmond Harrington, Kelly Rutherford, Michelle Trachtenberg, Penn Badgley, Margaret Colin, Blake Lively, Leighton Meester, Chace Crawford, Ed Westwick, Zuzanna Szadkowski, and Jeffrey Mowery in Gossip Girl (2007)

Kelly Rutherford and Robert John Burke in Gossip Girl (2007)

Kelly Rutherford, Leighton Meester, and Zuzanna Szadkowski in Gossip Girl (2007)

Kelly Rutherford in All My Husband's Wives (2020)

Kelly Rutherford, Erin Karpluk, and Kate Corbett in All My Husband's Wives (2020)

Kelly Rutherford and Kate Corbett in All My Husband's Wives (2020)

Kelly Rutherford and Erin Karpluk in All My Husband's Wives (2020)

Alyssa Milano and Kelly Rutherford in Melrose Place (1992)

Heather Locklear, Rob Estes, Kelly Rutherford, Josie Bissett, Thomas Calabro, John Newton, and John Reilly in Melrose Place (1992)

Linden Ashby and Kelly Rutherford in Melrose Place (1992)

Kelly Rutherford, Mario Lopez, and Rainn Wilson in The Stream (2013)

Natasha Henstridge, Tina Pehme, Kelly Rutherford, Vic Sarin, and Peyton List in A Sister's Nightmare (2013)

Kelly Rutherford and Peyton List in A Sister's Nightmare (2013)

Natasha Henstridge, Kelly Rutherford, and Peyton List in A Sister's Nightmare (2013)

Heather Locklear, Alyssa Milano, Linden Ashby, David Charvet, Rob Estes, Jamie Luner, Lisa Rinna, Kelly Rutherford, Thomas Calabro, Brooke Langton, Andrew Shue, and Jack Wagner in Melrose Place (1992)

Kelly Rutherford, Penn Badgley, Blake Lively, Taylor Momsen, Matthew Settle, Leighton Meester, Chace Crawford, and Ed Westwick in Gossip Girl (2007)