Clemenson's boyhood friend is his co-star in Bad Influence (1990) and Boston Legal (2004), James Spader.

Christian Clemenson appears with Jeff Bridges in both in The Big Lebowski (1998) where Clemenson plays "younger cop" and in The Fisher King (1991) where Clemenson's character Edwin murders Robin Williams' character's wife.

As of 2015, has appeared in three films that were nominated for the Best Picture Oscar: Hannah and Her Sisters (1986), Broadcast News (1987) and Apollo 13 (1995).

Appeared in two of the four series of CSI's franchise.