Eric Dane and Charles Parnell in The Last Ship (2014)

Eric Dane and Jocko Sims in The Last Ship (2014)

Patrick Dempsey, Jessica Capshaw, Eric Dane, Sara Ramirez, and Jesse Williams in Grey's Anatomy (2005)

Eric Dane and Chyler Leigh in Grey's Anatomy (2005)

Patrick Dempsey, Justin Chambers, Eric Dane, and Sara Ramirez in Grey's Anatomy (2005)

Patrick Dempsey, Katherine Heigl, Justin Chambers, Eric Dane, Brooke Smith, and Chandra Wilson in Grey's Anatomy (2005)

Patrick Dempsey, Eric Dane, and Kevin McKidd in Grey's Anatomy (2005)

Eric Dane, Chyler Leigh, and Jesse Williams in Grey's Anatomy (2005)

Eric Dane and Ellen Pompeo in Grey's Anatomy (2005)

Eric Dane, Chyler Leigh, Kevin McKidd, James Pickens Jr., and Chandra Wilson in Grey's Anatomy (2005)

Justin Chambers and Eric Dane in Grey's Anatomy (2005)

Eric Dane and James Pickens Jr. in Grey's Anatomy (2005)

Katherine Heigl, Eric Dane, Sara Ramirez, and Ben Vereen in Grey's Anatomy (2005)

Patrick Dempsey, Eric Dane, and James Pickens Jr. in Grey's Anatomy (2005)

Kate Walsh, Eric Dane, and Leven Rambin in Private Practice (2007)

Edward James Olmos and Eric Dane in One Fast Move (2024)

Eric Dane and KJ Apa in One Fast Move (2024)

Teri Polo and Eric Dane in The Ravine (2021)

Keri Russell, Eric Dane, and Andrew Kavovit in Married... with Children (1987)

Eric Dane in Married... with Children (1987)

Amanda Bearse, Eric Dane, and Andrew Kavovit in Married... with Children (1987)

Jessica Capshaw, Eric Dane, Chyler Leigh, Kevin McKidd, Sandra Oh, Ellen Pompeo, Sara Ramirez, and Chandra Wilson in Grey's Anatomy (2005)

Eric Dane and Marissa Neitling in The Last Ship (2014)

Eric Dane, Aaron Stanford, Omahyra, and Dania Ramirez in X-Men: The Last Stand (2006)

Eric Dane, Jocko Sims, and Kevin Michael Martin in The Last Ship (2014)

Adam Baldwin, Eric Dane, and Rhona Mitra in The Last Ship Prequel: Dr. Scott's Video Journal (2014)

Kathleen Robertson and Eric Dane in The Fixer (2015)

Adam Baldwin, Eric Dane, and Rhona Mitra in The Last Ship (2014)

Julia Roberts, Shirley MacLaine, Kathy Bates, Patrick Dempsey, Hector Elizondo, Queen Latifah, Anne Hathaway, Jessica Alba, Jessica Biel, Jamie Foxx, Jennifer Garner, Ashton Kutcher, Bradley Cooper, Eric Dane, Topher Grace, George Lopez, Emma Roberts, Taylor Lautner, Bryce Robinson, and Taylor Swift in Valentine's Day (2010)

Julia Roberts, Shirley MacLaine, Patrick Dempsey, Hector Elizondo, Queen Latifah, Anne Hathaway, Jessica Alba, Jessica Biel, Jamie Foxx, Jennifer Garner, Ashton Kutcher, Bradley Cooper, Eric Dane, Topher Grace, George Lopez, Taylor Lautner, Bryce Robinson, and Taylor Swift in Valentine's Day (2010)

Patrick Dempsey, Katherine Heigl, Kate Walsh, Justin Chambers, Eric Dane, Sandra Oh, James Pickens Jr., Ellen Pompeo, Sara Ramirez, Isaiah Washington, Chandra Wilson, and T.R. Knight in Grey's Anatomy (2005)