- Of all the characters she has played, Azula from Avatar: the Last Airbender (2005) and Daphne Blake from all the Scooby Doo productions she has been in are her favourites.
- She was a stand-up comedian before she became a voice actress.
- Voice actress, most notable as "Daphne Blake" on Scooby Doo programs, as well as "Princess Azula" on Nickelodeon programs.
- In her late teens, she entered the world of stand-up comedy on the advice of a close friend. In her comedy routine, she imitated voices very well and was advised to take a shot at voice acting.
- Frequently the voice of Daphne Blake in Scooby-Doo animated movies and video games
- She was considered for the role for Mother Gothel in Tangled.
- Has voiced both DC comics characters Lois Lane and Wonder Woman, both of whom have served as love interests for Superman/Clark Kent at different points - Lois usually being the default love interest while Wonder Woman filled the role in Else World stories such as Kingdom Come and more recently in DC's New 52 line. DeLisle voiced Lois in Justice League: Doom (2012) and Wonder Woman in JLA Adventures: Trapped in Time (2014).
- Has voiced two love interests for Marvel comics Mighty Thor - first she voiced the heroic Lady Sif in Hulk Vs. (2009) and then voiced the evil Amora the Enchantress on the Marvel Superhero Squad (2009) series.
- DeLisle played Commissioner Gordon's wife in two direct-to-video Batman films; his first wife, Barbara Gordon in Batman: Year One, and his second wife, Sarah Essen Gordon in Batman: The Dark Knight Returns Part 2.
- Participated with her musician husband in an episode of the TLC documentary program, A Wedding Story (2001), as Grey and Murry, which first aired in October 2002 on The Learning Channel.
- She was the voice of Derpy in the web video "Epic Rage Time: The Incredible Derp.".
- Has 3 children: a son Jefferson Texas Hammond (b.January 31, 2007) with her second ex-husband Murry Hammond; a son Harlan Roy Griffin (b.August 17, 2014) and a daughter Mariposa Ruth "Posie" Griffin (b.December 17, 2016) with her third ex-husband Jared Griffin.
- Fourth album, "Iron Flowers," released June 14, 2005.
- Is not on the best of terms with fellow voice artist Jim Cummings due to difference of political opinion.
- She auditioned for the role for Pearl Krabs in SpongeBob SquarePants.
- Touring in Europe in support of her fourth album, "Iron Flowers". (November 2005)
- Third album, The Graceful Ghost, released in March 2004.
- She is a lifelong Democrat.
- Survived an ectopic pregnancy in 2013.
- Best friends with April Stewart.
- Provided all the voices in the 2016 student film "Wendell's Advantageous Adversity", directed by future AromaPrime manager Liam Findlay.
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