Sarah Drew and Jesse Williams in Grey's Anatomy (2005)

Sarah Drew and Carly Peeters in Grey's Anatomy (2005)

Sarah Drew, Michael Weaver, Jesse Williams, La Monde Byrd, and Santiago Segura in Grey's Anatomy (2005)

Sarah Drew, Jesse Williams, and Santiago Segura in Grey's Anatomy (2005)

Sarah Drew, Michael Weaver, and La Monde Byrd in Grey's Anatomy (2005)

Sarah Drew, Michael Weaver, Jesse Williams, and Santiago Segura in Grey's Anatomy (2005)

Sarah Drew, Ellen Pompeo, Brandon Tyler Russell, and Branden Silverman in Grey's Anatomy (2005)

Sarah Drew, Jesse Williams, and Kelly McCreary in Grey's Anatomy (2005)

Justin Chambers, Marika Dominczyk, Sarah Drew, James Pickens Jr., and Camilla Luddington in Grey's Anatomy (2005)

Sarah Drew, Jesse Williams, and Chandra Wilson in Grey's Anatomy (2005)

Justin Chambers, Sarah Drew, James Pickens Jr., Ellen Pompeo, Caterina Scorsone, Chandra Wilson, Jerrika Hinton, Camilla Luddington, and Kelly McCreary at an event for Grey's Anatomy (2005)

Sarah Drew, James Pickens Jr., Ellen Pompeo, Jesse Williams, Camilla Luddington, and Kelly McCreary at an event for The 41st Annual People's Choice Awards (2015)

Sarah Drew, Lea Michele, and Jennifer Carpenter

Sarah Drew and Niall Matter in Christmas Pen Pals (2018)

Sean Astin, Patricia Heaton, Trace Adkins, Sarah Drew, Andrea Logan, and Shiloh Nelson in Moms' Night Out (2014)

Sarah Drew, Susan Johnson, Fran Kranz, Joel David Moore, Mark Steilen, Kenan Thompson, Sarah Wright, Suzanne Francis, Zachary Levi, and Gabe Grifoni in Wieners (2008)