The son of Mary Pickett, an American, and Antonio Gutierrez, Eduardo was born in January 6, 1942 in Manila. He studied at San Beda College and finished high school at San Sebastian College. He took up a course in Commerce at Letran College. He married actress Annabelle Rama, with whom he has six children, including actress Ruffa Gutierrez, who won a Miss World 1st Runner-Up in the '90s; child performer-twins 'Richard Gutierrez' and Raymond Gutierrez; Elvis Gutierrez, Rocky Gutierrez and Ritchie Paul Gutierrez, an up-and-coming rap artist. Eddie also had a son by actress Liza Lorena - Tonton Gutierrez; and Ramon Christopher, by singer-actress Pilita Corrales. A bit player in 'Prinsesang Gusgusin' (1958), Eddie was introduced in Handsome (1959) and played the lead in films like Kaming makasalanan (1960), 'Eddie Longlegs' (1964), Portrait of My Love (1965) and Pogi (1967). He was under contract for Sampaguita Pictures for eight years. His other films include 'Hiram na Kamay' (1962), 'June Bride' (1962), Pitong puso (1962), Sabina (1963), Bird of Paradise (1963), 'Eddie Loves Susie' (1964), 'Isinulat sa Dugo'1965), 'I'll Dream of You' (1966), and All Over the World (1967). After living in the United States for several years, he came back to the Philippines with his family and resumed his acting career. He appeared in Katawang lupa (1975), 'Ursula' (1976), 'Beerhouse' (1977), Bontoc (1977), 'Balatkayo' (1978), Bomba Star (1978), Sari-saring ibong kulasisi (1978) , Lagi na lamang ba akong babae? (1978), and 'Lumakad Ka, Gabi' (1979). In 1991, Eddie was nominated Best Supporting Actor by the Film Academy of the Philippines (FAP) for Uubusin ko ang lahi mo (1991). He received the FAP award for Best Actor and the Filipino Academy of Movie Arts & Sciences (FAMAS) for Best Supporting Actor for Only You (1992). In 2004 and 2006, Eddie joined the cast of the TV fantasy series, "Mulawin" and "Majika," in both series playing an elder with magical powers.