Bryan Cranston and Jane Kaczmarek in Malcolm in the Middle (2000)

Jane Kaczmarek in Malcolm in the Middle (2000)

Jane Kaczmarek and Edie McClurg in Malcolm in the Middle (2000)

Justin Berfield, Bryan Cranston, Jane Kaczmarek, and Erik Per Sullivan in Malcolm in the Middle (2000)

Jane Kaczmarek and Bradley Whitford in Malcolm in the Middle (2000)

Jane Kaczmarek and Jessica St. Clair in Playing House (2014)

Jane Kaczmarek, Norma Michaels, and Jessica St. Clair in Playing House (2014)

Gerry Bednob, Jane Kaczmarek, Norma Michaels, Lennon Parham, Jessica St. Clair, and Brad Morris in Playing House (2014)

Pierce Brosnan, Delta Burke, Jane Kaczmarek, Clara Perryman, and Monique van de Ven in Remington Steele (1982)

Kurt Fuller, Jane Kaczmarek, Jason Ritter, and Dustin Ybarra in Us & Them (2014)

Jane Kaczmarek and Whitney Cummings in Whitney (2011)

Elijah Wood, Jane Kaczmarek, and Jason Gann in Wilfred (2011)

Bruce Boxleitner, Kate Jackson, James Edgcomb, and Jane Kaczmarek in Scarecrow and Mrs. King (1983)

Kate Jackson, Anthony Gordon, and Jane Kaczmarek in Scarecrow and Mrs. King (1983)

Jane Kaczmarek in Scarecrow and Mrs. King (1983)

Jane Kaczmarek, Betsy Brandt, and Patrick Mulvey in Killing Eleanor (2020)

Pierce Brosnan, Delta Burke, Jane Kaczmarek, and Carole White in Remington Steele (1982)

Justin Berfield and Jane Kaczmarek in Malcolm in the Middle (2000)

Frankie Muniz and Jane Kaczmarek in Malcolm in the Middle (2000)

Bryan Cranston, Jane Kaczmarek, and Erik Per Sullivan in Malcolm in the Middle (2000)

Kaley Cuoco and Jane Kaczmarek in The Big Bang Theory (2007)

Jane Kaczmarek in The Big Bang Theory (2007)

Johnny Galecki and Jane Kaczmarek in The Big Bang Theory (2007)

Jane Kaczmarek in Big Time in Hollywood, FL (2015)

Jane Kaczmarek in Law & Order: Special Victims Unit (1999)

Kate Jackson, Beverly Garland, Jane Kaczmarek, and Ed Vandell in Scarecrow and Mrs. King (1983)

Camryn Manheim, David Eigenberg, Jane Kaczmarek, Chris Mulkey, Jenny O'Hara, Thomas Sadoski, Annika Marks, and Betsy Brandt in Killing Eleanor (2020)

Laura San Giacomo, Annabella Sciorra, and Jane Kaczmarek in Jenifer (2001)

Jane Kaczmarek and Rebecca Williams in Reviving Ophelia (2010)

Sarah Jessica Parker, Debrah Farentino, James Wilder, George DiCenzo, Jane Kaczmarek, Kathleen Lloyd, Barry Miller, Joe Morton, and Jon Tenney in Equal Justice (1990)

Mark-Paul Gosselaar, Gloria Reuben, Natalia Cigliuti, Jane Kaczmarek, J. August Richards, Melissa Sagemiller, and Jonathan Scarfe in Raising the Bar (2008)

Jane Kaczmarek and Sander Vanocur in Without Warning (1994)