- Twin brother of actor Jason London.
- His younger sister, Dedra London, died in a car accident in 1992 at the age of 16.
- When Jeremy was not available to shoot I'll Fly Away: Then and Now (1993), his identical twin brother Jason London played the part of Nathaniel Bedford.
- Plays guitar and drums with brother Jason London.
- Godmother of his son Lyrik, is Carmen Electra.
- He played Joey Lauren Adams's ex-boyfriend in Mallrats (1995) while his identical twin brother Jason London played her boyfriend in Dazed and Confused (1993). Coincidentally, Ben Affleck also appeared in both films.
- His brother Jason London was in the 7th Heaven (1996) episode Smoking (2003) playing "Sid Hampton", Chandler's twin brother.
- Father, with Melissa Cunningham, of son, Lyrik London, born on 10 March 2007.
- Directed Secrets Through the Smoke (2001), an educational film featuring Dr. Jeffrey Wigand, the former tobacco-company executive and subject of the Academy Award-nominated film, The Insider (1999). In it, Dr. Wigand shares his experiences with the tobacco industry's manipulation of the truth.
- In a relationship with actress Juliet Reeves London (2013-present).
- Second child, Wyatt Finn London, was born on June 5, 2014, with wife Juliet Reeves London.
- Was voted Most Talented Male in high school.
- Has also written and directed two anti-smoking public service announcements with his twin brother, Jason London, one titled "Suffering" and the other titled "Anniversary."
- He and his identical twin brother Jason London made guest appearances on The Outer Limits (1995).
- Played Professor Harold Hill in his high school's production of "The Music Man."
- Proposed to Melissa Cunningham, on December 23, 2005, with a three-carat princess-cut diamond ring.
- Married at the Hidden Chateau and Garden in West Hills, California.
- Ex-brother-in-law of Charlie Spradling.
- Wife, Melissa Cunningham is expecting their first child, due early Spring 2007.
- Brother-in-law of Sofia Karstens.
- Wore a Hugo Boss suit at his wedding.
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