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Isis Nile is of Egyptian and German ancestry. She grew up in Sherman Oaks, CA, in the San Fernando Valley and attended a Roman Catholic school. She was working as a makeup artist before entering the porn business in July 1993 with Ed Powers' More Dirty Debutantes 28 (1993). Her exotic looks quickly made her very popular and she performed in over 100 hardcore features before leaving the industry in 1995. In 1997 she was stripping at clubs across North America.

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