Pavone's career began in 1962 when she won the first edition of the "Festa degli Sconosciuti" (Unknown performing artist contest), organized by famous singer Teddy Reno, who later became her husband and manager. In the following decade she became one of the most famous international stars, with Top-10 songs like "Datemi un Martello," "Viva La Pappa Col Pomodoro," and "Cuore," which entered the UK charts in 1966.