Jesse Spencer in The Girl Is in Trouble (2015)

David Eigenberg, Jesse Spencer, Christian Stolte, Monica Raymund, Joe Minoso, and Yuriy Sardarov in Chicago Fire (2012)

Jesse Spencer and Monica Raymund in Chicago Fire (2012)

Omar Epps and Jesse Spencer in House (2004)

Jennifer Morrison and Jesse Spencer in House (2004)

Omar Epps, Hugh Laurie, Jennifer Morrison, and Jesse Spencer in House (2004)

Nicholas D'Agosto and Jesse Spencer in House (2004)

Sharif Atkins, Arlen Escarpeta, Peter Jacobson, and Jesse Spencer in House (2004)

Jesse Spencer and Charlyne Yi in House (2004)

Omar Epps, Hugh Laurie, Jesse Spencer, Odette Annable, and Charlyne Yi in House (2004)

Mena Suvari and Jesse Spencer in Chicago Fire (2012)

Jesse Spencer, Christian Stolte, Taylor Kinney, and Yuriy Sardarov in Chicago Fire (2012)

David Eigenberg, Jesse Spencer, Charlie Barnett, and Monica Raymund in Chicago Fire (2012)

Omar Epps, Jesse Spencer, Odette Annable, and Charlyne Yi in House (2004)

Omar Epps, Vinessa Shaw, Peter Jacobson, and Jesse Spencer in House (2004)

Jesse Spencer and Taylor Kinney in Chicago Fire (2012)

Jesse Spencer and Eamonn Walker in Chicago Fire (2012)

Jesse Spencer and Kamal Angelo Bolden in Chicago Fire (2012)

Jesse Spencer, Taylor Kinney, and Monica Raymund in Chicago Fire (2012)

Lauren German, Jesse Spencer, Eamonn Walker, Charlie Barnett, Taylor Kinney, and Monica Raymund in Chicago Fire (2012)

Robert Sean Leonard, Omar Epps, Lisa Edelstein, Peter Jacobson, Hugh Laurie, Jennifer Morrison, Kal Penn, Jesse Spencer, and Olivia Wilde in House (2004)

Robert Sean Leonard, Omar Epps, Lisa Edelstein, Hugh Laurie, Jennifer Morrison, and Jesse Spencer in House (2004)