Son of John Wayne and Josephine Alicia Saenz.
Half-brother of Ethan Wayne, Aissa Wayne, and Marisa Wayne.
Stepson of Pilar Wayne. Brother of Michael Wayne, Toni Wayne and Melinda Wayne. Half-brother of Ethan Wayne, Aissa Wayne, and Marisa Wayne. Uncle of Brendan Wayne. Nephew of Robert E. Morrison.
Was offered the role of Superman in the Superman (1978) film but declined because of his father's cancer.
Met his second wife, Misha Anderson, at a mutual friend's daughter's wedding at the Sherwood Country Club.
Fifteen year-old Wayne was big for his age and able to pass as a cadet in John Ford's "The Long Grey Line.".
"Big Jake" was the ninth and last of his co-starring roles with his father.
Among the summer stock and dinner theater productions Wayne starred in included 'My Three Angels," "Angel on my Shoulder," "Romantic Comedy," "Come Blow Your Horn," and "Arsenic and Old Lace" at the Burt Reynolds Theatre in Florida, which reunited him with Henry Brandon, his co-star in "The Searchers.".
The February 6, 1985, issue of Variety announced the film "Ombre sul ponte" (English title "Shadow on the Bridge") would begin filming in March 1985, with director Ruggero Deodato, starring Franco Nero, Patrick Wayne, Lisa Blount, and Eli Wallach. No evidence the film was ever made or released.