Parents are Honduran.
Is the youngest of 6 siblings.
Started acting in community theater and school plays at the age of eight.
Attended the University of Southern California where she studied International Relations.
Two of her films, Lords of Dogtown (2005) and The Sisterhood of the Traveling Pants (2005), opened in the United States on the same day: Friday, June 3, 2005.
During an interview with her The Sisterhood of the Traveling Pants (2005) co-star Alexis Bledel for Latina Magazine, she was stunned to discover that Alexis speaks Spanish and had throughout production of the film.
Went to Calabash Elementary School in the San Fernando Valley from 1994-1995 where she played one of the lead characters in her 5th grade graduation play called "Oliver." She played the "Artful Dodger" in the production.
Lloyd's of London has insured America's smile for $U10 million.
Ranked #84 on the Maxim magazine Hot 100 of 2008 list.
Was allegedly cast in the lead role in An Invisible Sign (2010), but was replaced by Jessica Alba before filming began.
One of People Magazine's 100 Most Beautiful People. 
One of Time magazine's 50 Most Influential People in 2006.
Shooting for The Sisterhood of the Traveling Pants 2 (2008). 
Playing "CB's Sister" in the Off-Broadway play, "Dog Sees God: Confessions of a Teenage Blockhead", at the Century Center for the Performing Arts (New York, NY). [December 2005]
Starring and playing the lead role in ABC's Ugly Betty (2006) (aka "Betty La Fea" - USA) as "Betty Suarez". It's a modern tale of the ugly duckling fairy tale. [September 2006]
She has the same first name as her mother.
(June 27, 2011) Married her boyfriend of 6 years Ryan Piers Williams following a year-long engagement.
Has a son, Sebastian Piers Williams (b. May 29, 2018), with her husband Ryan Piers Williams.