Lupita is a graduate of the Yale School of Drama.
It is a Luo tradition to name a child after the events of the day, so her parents named her Lupita, because of her Mexican birth. She is the second of six children.
Born in Mexico City, Mexico, to Kenyan parents. Her father, Professor Anyang' Nyong'o, is a senator in Kenya.
Is the fourth Mexican-born actress to be nominated for an Oscar. The others, in chronological order, are: Katy Jurado for Broken Lance (1954), Salma Hayek for Frida (2002) and Adriana Barraza for Babel (2006).
When she won the Oscar for Best Actress in a Supporting Role for her role in 12 Years a Slave (2013) in 2014, she became the first Kenyan to win an Oscar, the first African actress to win Best Actress in a Supporting Role and the first Mexican-born actress to win an Oscar.
Considers herself Mexican-Kenyan.
Is fluent in Luo, English, Swahili and Spanish.
Her brother, Junior, was her date to the Oscars in 2014.
Is of Luo descent on both sides of her family.
Moved from Mexico back to Kenya with her family when she was less than a year old.
Her father, Peter Anyang' Nyong'o, a former college professor, was elected to represent Kisumu County in the Kenyan Senate in 2013.
Her mother, Dorothy Ogada Buyu Nyong'o, is the managing director of the Africa Cancer Foundation and has her own communications company.
Was the 142nd actress to receive an Academy Award; she won the Best Supporting Actress Oscar for 12 Years a Slave (2013) at The 86th Academy Awards on March 2, 2014.
Unveiled as the "Face of Lancôme" becoming the first black celebrity to represent the French luxury cosmetic brand. She is the fourth Academy Award-winning actress to merit this post after Julia Roberts, Penélope Cruz and Kate Winslet. [April 2014]
Her first "Vogue" magazine cover (July 2014) was photographed by Swedish photographer Mikael Jansson.
Was originally cast as Angela Rivera in Southpaw (2015), but was replaced by Naomie Harris after dropping out of the project.
Is one of 13 actresses who won their Best Supporting Actress Oscars in a movie that also won the Best Picture Oscar (she won for 12 Years a Slave (2013)). The others are Hattie McDaniel for Gone with the Wind (1939), Teresa Wright for Mrs. Miniver (1942), Celeste Holm for Gentleman's Agreement (1947), Mercedes McCambridge for All the King's Men (1949), Donna Reed for From Here to Eternity (1953), Eva Marie Saint for On the Waterfront (1954), Rita Moreno for West Side Story (1961), Meryl Streep for Kramer vs. Kramer (1979), Juliette Binoche for The English Patient (1996), Judi Dench for Shakespeare in Love (1998), Jennifer Connelly for A Beautiful Mind (2001) and Catherine Zeta-Jones for Chicago (2002).
In 2014, was chosen by People Magazine as the World's Most Beautiful woman.
Second Vogue cover appearance: October 2015.
Shared the cover of Vanity Fair magazine's 2016 Hollywood issue with, Jane Fonda, Viola Davis, Cate Blanchett, Jennifer Lawrence, Rachel Weisz, Charlotte Rampling, Brie Larson, Alicia Vikander, Gugu Mbatha-Raw, Helen Mirren, Diane Keaton and Saoirse Ronan. Photographed by Annie Leibovitz.
Nominated for the 2016 Best Leading Actress in a Play Tony Award for her performance in "The Eclipsed". She lost the award to Jessica Lange for her performance in "Long Day's Journey into Night".
The N and G in her surname are actually silent.
Is frequently the subject of famed photographer duo Mert Alas & Marcus Piggott.
Resides in Brooklyn, New York. 
Ranked as having one of the "Most Beautiful Famous Faces" by TC Candler's list of the "100 Most Beautiful Famous Faces From Around the World" for 4 consecutive years. She was ranked #17 in 2016, #11 in 2015 and #3 in 2014 and #26 in 2014.
First Kenyan actress to be nominated for, and to win, an Academy Award.
Attributes her career choice to British actor Ralph Fiennes. While she was a production assistant on The Constant Gardener (2005) during the Nairobi/Kenya leg of the shoot, she asked Ralph for advice on becoming an actress and he told her that it was tough, but that if acting was what she really wanted to pursue, she simply had to persevere. Eight years later, after attending a screening of 12 Years a Slave (2013) at the Telluride Film Festival in August 2013, Lupita approached Ralph afterwards wondering if he'd remember her. He did, instantly, but he had no idea that she was the character Patsey whose performance had blown him away minutes earlier.
As of 2019, has appeared in two films nominated for the Best Picture Oscar, 12 Years a Slave (2013) and Black Panther (2018).
Her father was a political enemy of Daniel arap Moi, the President of Kenya from 1978 to 2002. Her uncle Charles, her father's brother, died in a fall from a boat, possibly as a murder to intimidate Lupita's family.