Tovino Thomas was born in a Syro-Malabar Catholic Nasrani family in Irinjalakkuda, Kerala, India. He completed his schooling from Don Bosco High School, Irinjalakuda and graduated from Tamil Nadu College of Engineering, Coimbatore, Tamil Nadu. He served as a Software Enginner at Cognizant Technology Solutions before being introduced into the Malayalam film industry.
Tovino made his silver screen debut through the Malayalam film Prabhuvinte Makkal (2012) directed by Sajeevan Anthikad. His onscreen performances in his subsequent films, ABCD (2013), 7th Day (2014), Ennu Ninte Moideen (2015) and Charlie (2015), made him to be considered as one of the most promising actors. He acted in the lead role in the film Guppy (2016) and was highly acclaimed by the critics. His subsequent films Oru Mexican Aparatha (2017) and Godha (2017) went on to become huge hits in the Mollywood industry.
Tovino got married to Lidiya at St. Thomas Syro-Malabar Catholic Cathedral, Irinjalakuda on 25 October 2014. His wife is also from a Syrian Catholic Nasrani family in Kerala. They have a daughter.