If you care to find “Wicked,” look to the top of box office charts. Universal’s adaptation of Act One (with some padding) of the popular Broadway musical was No. 1 in North America with $114 million from 3,888 theaters over the weekend.

Those dazzling ticket sales rank as the third biggest domestic debut of the year behind “Deadpool & Wolverine” ($211 million) and “Inside Out 2” ($154 million). Among other benchmarks, “Wicked” landed the fourth-biggest start in history for a musical, ahead of Disney’s recent “The Little Mermaid” remake ($95.5 million) and behind “Frozen II” ($130 million), as well as the best opening (by far) for a Broadway adaptation, overtaking the record held by 2014’s “Into the Woods” ($31 million).

“Wicked” collected an additional $50.2 million at the international box office, bringing its global tally to $164.2 million. It marks the biggest worldwide opening for a film based on a Broadway show, supplanting another Universal musical, “Les Miserables,...