Ron Ellis's and Sarah Pillsbury's Oscar-winning "Board and Care" looks at a pair of Down's Syndrome-afflicted youths trying to connect with each other. There's probably no way for us to imagine what it must be like to live with this condition, but these youths make an effort to connect, despite people wanting to keep them apart.
Obviously this isn't the most readily available documentary, but you can find it on Vimeo (a lesser-known version of YouTube). Ellis posted it to his account there, preceded by footage of him and Pillsbury winning the Oscar for it and bringing Laura with them to the stage.
I should note that while this is a documentary, some of the characters are people playing roles. One is Luana Anders, who co-starred in "The Pit and the Pendulum" (1961) and "Easy Rider" (1969).
Definitely check it out.
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