"I've Gotta Have You" (music by Harry Warren, lyrics by Mack Gordon), sung by June Havoc, was deleted from the movie. Miss Havoc's prerecording was released 1976 on the Out Take Records LP (which later would be reissued by DRG), "Cut! Out Takes From Hollywood's Greatest Musicals, Volume One."

"Lux Radio Theater" broadcast a 60 minute radio adaptation of the movie on November 15, 1943 with Alice Faye reprising her film role and Robert Young in the John Payne part.

A memo to the exchange managers and exhibitors (and sniped to 20th Century Fox's press book) reads: "CORRECTION! Please eliminate the following credits on "Hello Frisco, Hello": George Barbier... from the cast. Hermes Pan... as co-stager of the dance sequences."

The movie is a remake of King of Burlesque (1936), starring Warner Baxter. Alice Faye and Jack Oakie play the same roles (i.e. the "heroine" and the "hero's sidekick") that they played in the previous film.

"The Screen Guild Theater" broadcast a 30 minute radio adaptation of the movie on April 3, 1944 with Jack Oakie reprising his film role.

After Mayor Angelo J. Rossi complained that "Frisco" was an inappropriate contraction of his city's name, 20th-Century Fox agreed that whenever it was shown in San Francisco and its suburbs, the film would be renamed, "Hello, San Francisco, Hello".

Both Koo Payne and Lynn Mardi were born in Roanoke, VA.