Percy Waram was the only member of the original Broadway cast of "The Late George Apley" to repeat his role onscreen.
Twentieth Century Fox bought the rights to the play for $275,000 ($3.78M in 2017).
The song 'Sweet Little Marigold,' sung by Agnes Willing (Vanessa Brown) at the Thanksgiving dinner party, is missing from the 20th Century Fox television print aired on Turner Classic Movies, possibly because of legal issues involving the music rights.
The New York City street scenes were filmed at the Warner Bros. lot in Burbank, California.