Peter Sallis (Cleggy) is the only actor to appear in all 295 episodes of the series. In second place is Jane Freeman, who appeared in 274 episodes.

The series has been officially declared the world's longest-running television sitcom, airing continuously between Wednesday 4th January 1973 to Sunday 29th August 2010. Peter Sallis was the sole cast member to appear (as Norman Clegg) throughout the whole 31 seasons. He also appeared (as Clegg's father) in the spin-off prequel series First of the Summer Wine (1988).

Officially announced by Buckingham Palace in 1996 as being Her Majesty the Queen's favourite television series.

By 1976 it was clear that Michael Bates was ill. The cancer which was to eventually kill him meant the strenuous walking through the hills became impossible. He was written out of the series and his noticeable gap was filled by Brian Wilde, who had already become known as Mr. Barrowclough in Porridge (1974). Michael Bates did continue to appear in his other success, It Ain't Half Hot Mum (1974), but died soon after.

In 2008 it was reported the series had been axed due to low viewing figures. The BBC confirmed another season had been commissioned, but the series was still axed in 2009.

Tom Owen, apparently had a very poor relationship with co-star Kathy Staff, claiming in a newspaper interview, that she constantly criticised and complained about him to other cast members behind his back.

Holmfirth was chosen as the setting for Last of the Summer Wine after Barry Took made a programme about Working Men's Clubs at nearby Burnlee WMC. When producer James Gilbert was looking for a location for an episode of Comedy Playhouse (1961), Barry Took recommended Holmfirth. That episode was developed into the series "Last of the Summer Wine".

The long-running series generated such a devout worldwide following, a special tour operation evolved over the years affording fans and visitors the opportunity to explore the actual series locations and enjoy the picturesque surroundings.

Although Ivy is a regular character throughout the whole run - and alongside her husband Sid for the first seven series - the couple's surname is never mentioned.

In May 2009, Peter Sallis (Clegg) revealed that the programme was nearly cancelled before it had even started, when Bill Owen (Compo) who was very left-wing and Michael Bates who was very right-wing started having a heated and vigorous argument about their different political affiliations, over dinner when they first met. Producer James Gilbert read them the riot act and told them that unless they agreed to differ, and not to argue about politics, he was going to cancel the project. Owen and Bates meekly agreed and never discussed politics again.

By 1982, it was the BBC's most popular sitcom with 16 million viewers.

Brian Wilde much preferred working with Director Sydney Lotterby ( who had directed Wilde in Porridge) rather than Alan J.W. Bell due to the difference in directing and visual styles of the two men. Bell liked to shoot in a more cinematic way often using long distance wide shots of the Yorkshire landscape and hills with the actors walking through them playing the scene. Inevitably this meant scenes took a lot longer to set-up ,co-ordinate and shoot much to Wilde's and some other cast member's frustration whereas Lotterby tended to keep things much tighter visually, like a traditional sitcom and worked more quickly.

In " The 30's Car" Clegg is reading a Holmfirth newspaper which is from the filming location as compared to the show being set in Yorkshire.