Thames TV received letters from epileptics complaining that the opening sequence of the show was causing them to have seizures.

"Jaunting", the term used for teleporting in this series, comes from the novel "The Stars My Destination" (British title "Tyger Tyger") by Alfred Bester.

The Tomorrow People became Thames TV's replacement for the Ace Of Wands series, another children's series which also explored the supernatural and fantasy.

Actor Nicholas Young confessed in the DVD commentary that he got the role of John because he cheated. He was working part-time for his agent at the time. When he saw the breakdowns for the role of John, he thought he'd be perfect for that role. Nicholas was responsible for sending over the head shots and resumes of several actors to be considered for the role of John. So Nicholas would send one head shot and resume of each actor (his competition for the role he wanted) and twelve of his own head shots and resumes as well. Although that's in the gray area of ethics, it did get him an audition and two call backs. The directors weren't too keen on Nicholas, but seeing as he was the only actor over the age of eighteen, they compromised on their idea of the perfect John and eventually cast Nicholas for the part.

During the majority of the series, when the lab was located in the abandoned underground station, the control panel for the entrance was a prop that previously appeared in Doctor Who: The Ark in Space: Part One (1975)). The prop was originally made for UFO (1970), and other panels and control desks from that series can occasionally be seen in both Doctor Who and The Tomorrow People.

The series was publicised as ITV's answer to the BBC's popular science-fiction series Doctor Who (1963), although it had an even lower budget and production values. An early publicity photograph included Nicholas Young, Peter Vaughan-Clarke, Sammie Winmill and Stephen Salmon pictured with Jon Pertwee, who was starring as the Third Doctor when The Tomorrow People made its debut.

According to interviews in the DVD commentary, the character of Kenny was quickly written out of the series due to actor Stephen Salmon's poor dramatic ability and an inability to act in general. Salmon would frequently forget lines and spoke with a drawl, making him to difficult to understand by the other actors. For this reason, Kenny's character is seldom seen "in the action" after the pilot, with Kenny often guarding the lab or visiting his home during the bulk of the series.

Director Paul Bernard pioneered the use of yellow, rather than the more normal blue or green, as the background colour to be replaced by filmed inserts for Chromakey (Colour Separation Overlay) special effects. This allowed the Tomorrow People's suits to have blue piping which would have appeared invisible (ie the background picture would have shown through) if a blue background and keying had been used.

The term "homo superior", which is used to describe the Tomorrow People, had appeared in David Bowie's 1971 song "Oh! You Pretty Things". The song was from his "Hunky Dory" album and had been a chart hit for Peter Noone.

During series 2:1 "The Blue and the Green", stock footage of the riots in Northern Ireland and 1968 riots in Paris were used to depict "The Blue and the Green" riots across the world.

Actress Sammie Winmill (Carol) decided not to renew her contract after the first series to pursue bigger and better opportunities.

Nicholas Young stated on the DVD commentary that he couldn't understand a word Misako Koba was saying.