Three nubile young prison inmates -- fiery Carrie (slinky blonde Jillian Kesner), sassy Chicago (lovely eyeful Janice Heiden), and fragile Mitzi (foxy brunette June Fairchild) -- are chosen for an unorthodox college study on human behavior that's being conducted by shrink Professor Blalock (a solid turn by Warren Stevens). Unbeknownst to the gals, they are really being used as guinea pigs for an experimental drug that causes all of them to become more exceedingly hostile and unstable: Mitzi steals a giant stuffed penguin from a toy store display window, Chicago becomes aggressively libidinous, and Carrie suddenly develops a moral conscience. Ably directed with flair to spare by underrated 70's B-movie master Gus ("Nashville Girl") Trikonis, with a pleasing plenitude of tasty distaff nudity, a smidgen of soft-core sex, several cool set pieces (highlights include a rough'n'tumble catfight in an all-girls juvenile penitentiary, a rowdy pool party, and a smoky back alley high stakes craps game), a tight'n'trim 75 minute running time, profane dialogue, a pertinent central message about the dangers of unethical unregulated drug testing, and a winningly raunchy sense of breezy'n'easy irreverent humor, this flick serves up loads of infectiously trashy grindhouse fun. The three lady leads are hot, sexy and attractive (Fairchild in particular is absolutely adorable), plus they all are pretty capable actresses. This movie further benefits from spirited acting by an enthusiastic supporting cast: Peter Hooten as Blalock's hunky nice guy son Carter, Judith Roberts as the shrewish Ms. Blalock, Vic Jolley as the girls' uptight guardian Vernon, David Ankrum as the nerdy Leroy, and Faith Barnhart as the snippy Sharon. The always reliable Gary Graver's typically proficient cinematography does the trick. The groovy 70's cop show-style disco score by Don Bagley and Steve Michaels likewise hits the funky spot. A hugely entertaining and unjustly overlooked exploitation blast.