Ted Knight played cartoonist, Henry Rush, who lives with his photographer wife, Muriel, in a two family home in San Francisco, California. The series opens up with the loss of their downstairs tenant, Mr. Rafkin, who was a transvestite. Selma Diamond played his sister. Henry and Muriel's adult daughters, Jackie and Sara, lived with them in their two bedroom apartment upstairs. It would be sensible for the girls as they were called to move downstairs. The actresses who played the daughters were fine. Nancy Dussault is ideal as Muriel. Jim J. Bullock played the annoying Monroe Ficus. While there were plenty of memorable moments between Monroe and Henry, there were tender moments between him and Muriel and his daughters. Audrey Meadows joined the show as Muriel's adopted mother. There were lots of friendly, light moments mixed with heavy issues as well. But there was a general tenderness there that isn't in today's sitcoms.