Chris Barrie's dead-on impersonation of Ronald Reagan was so well known, he reprised the role in the 1985 song "Two Tribes" by Frankie Goes to Hollywood.

The series' first benefactor was Clive Sinclair, who funded the initial puppet development costs to the tune of £20,000, although he pulled out before the first pilot episode was made. The series made a puppet of him.

This show brought together Rob Grant, Doug Naylor, and Chris Barrie, who would team up to create Red Dwarf (1988).

David Tennant appears as one of the Humans in the "Some of our Puppets are missing" sketch.

One of the generic puppets used as an extra in many scenes was a Lord Lucan look-alike. He would often appear as a waiter, barman or just in the background of many sketches in foreign settings. The real Lord Lucan Vanished without trace in 1974 on suspicion of murdering the family nanny and there had been numerous unsubstantiated sightings of him published in the press for years afterwards.

The puppets from this show starred in the music video for "Land of Confusion" by Genesis. The video centered around Ronald Reagan (as voiced by Chris Barrie), but also featured most of the Spitting Images characters in one way or another.

One of the longest running British TV comedies in history. The show ran for 12 years.

The Liberal party leader David Steel was mercilessly satirised as being obsessed with and literally in the pocket of SDP leader (and later the SDP/Liberal Alliance's) David Owen. Steel later claimed the show's depiction of him as Owen's fawning sidekick seriously and irreparably damaged his credibility and reputation as a politician.

In an episode of 'Alan Davies: As yet untitled' Stephen Fry revealed that the late Diana Princess of Wales was a big fan of the show.

The producers responded to John Major's bland, undemonstrative persona by making his puppet completely gray.

Magician Paul Daniels had no objections to the show poking fun at him wearing a toupee. However, he did object to sketches involving him nuzzling the breasts of his assistant and eventual wife Debbie McGee, as they went against his family-friendly persona.

Although the program satirized British politics and popular culture, it also influenced them as well. In Parliament, Prime Minister John Major received catcalls about peas, based off his character's fondness of the vegetable. David Steel's political image was damaged in sketches with him in the pocket of David Owen.

In the series, John Major is portrayed as having an unrequited crush on fellow Conservative Party colleague Virginia Bottomsley. In real life, John Major did have an affair during his time as Prime Minister, ironically with Conservative MP Edwina Currie.

In Buckingham Palace sketches, a court flunky named Muriel is often seen informing the royal family about goings-on. The puppet used for him was a caricature of 18th-Century political cartoonist James Gillray, who was well-known in his time for creating satirical illustrations poking fun at Napoleon, King George IV, and George Macartney.