I was thinking about this show recently and I decided to see if I could find some episodes for sale. I found some on Amazon and I just finished watching "Ramona the Patient" a few minutes ago! It was really fun to realize that I could still hum along with the theme music and remember the cat book report that she does at the end.
This show was on in the late 80's, and it aired on Sunday mornings for a while if I remember correctly. I was about 6 and I loved it because I was always a huge fan of Beverly Cleary books. The show itself is pretty good, and it does remain loyal to the stories. It's also fun to see Sarah Polley in such a cute role, as she's known to play very serious, somber roles these days.