Only six stories (the pilot Anna Lee: Headcase (1993) and the five episodes of this series) were filmed. Author Liza Cody stopped writing Anna Lee mystery novels because of the television movies. The rights had already been purchased for any future Anna Lee novels that she might write, but this did not allow writers to write any original stories that were not based on her novels. However because she was unsatisfied with the way that the previous books had been adapted, she said she wouldn't write any more of them, preventing further episodes being made; instead she focused on the Eva Wylie books.
Four major characters were played by different actors from those who played them in the pilot Anna Lee: Headcase (1993). These were: Commander Martin Brierly (Michael Bryant in the pilot; John Rowe in the series), Beryl Doyle (Barbara Leigh-Hunt in the pilot; Sonia Graham in the series), Bernie Schiller (Ken Stott in the pilot; Peter Wight in the series) and Stevie Johnson (David Harewood in the pilot; Wil Johnson in the series).