Frasier: [responding to a caller] Roger, at Cornell University they have an incredible piece of scientific equipment known as the Tunneling Electron Microscope. Now, this microscope is so powerful that by firing electrons you can actually see images of the atom, the infinitesimally minute building blocks of our universe. Roger, if I were using that microscope right now, I still wouldn't be able to locate my interest in your problem.
Frasier: Hello, Ethan. I'm listening.
Ethan: Hi, Dr. Crane.
Frasier: How old are you?
Ethan: I'm thirteen.
Frasier: Well, what can I do for you?
Ethan: Well, I'm having a lot of problems with the other kids at school. They're always beating me up.
Frasier: Why do you think that's so?
Ethan: Probably because I'm smart. I have a 160 IQ. I'm in the astronomy club and I hate sports.
Frasier: Well, you know, Ethan, the other children are just acting out of jealousy and immaturity, and I know it doesn't help much right now, but the day will come in the next few years when you will have the last laugh.
Ethan: ...That's it?
Frasier: [surprised] Yes.
Ethan: Frankly, Dr. Crane, I find that advice patronizing, simplistic and, in all candor, uninspired. The real surprise here is that they pay you to dole out this balloon juice.
Frasier: Ethan, where are you calling from?
Frasier: Well, if any of Ethan's classmates are listening, you know where he is, and he can't stay in there forever. Thank you for your call.
Frasier: Niles, have you been self-medicating again?
[Looking through a box of keepsakes from Niles' childhood]
Martin: Oh, no one around here draws pictures anymore.
Martin: What the heck is this, anyway?
Niles: Oh, that is an Egyptian battle scene from AÔda. Look, that's Radames, and that's the jealous Amneris, and -
Niles: Oh, I misspelled Amonasro. Ah, to be six again...
[Niles watches Martin working out a chess problem]
[Martin reaches for another piece]
Martin: All right, what would you do?
Niles: Well for starters, I'd take that corn-nut off the board.
Martin: That corn-nut's my bishop. Eddie ate the real one.
Niles: In that case, Corn-nut to Rook Seven.
Frasier: And though washing one's hands twenty to thirty times a day would be considered obsessive/compulsive, please bear in mind that your husband is a coroner. Thank you for your call, Jeanine. Roz, whom do we have next?
[Buldog is doing his radio show]
Bulldog: [to a caller] Well Chuck, I'm really sorry I offended you. Now why don't you put your skirt back on and do some dishes?
[Frasier is trying to get Bebe to quit smoking]
Frasier: For God's sake... I don't care anymore. You know, I can't help you, nobody can. You want to ruin it for both of us? Here...
[tosses her a lighter]
Frasier: ... go ahead, knock yourself out.
[Bebe begins to light cigarette]
Frasier: I only wish I could be there when it happens.
Bebe: When what happens?
Frasier: When you see that newspaper headline: "Big Willy Boone, Millionaire, Dead." Oh, how I wish I could be there when you watch the funeral on the news. Watch the casket being slipped into the ground. Only, you won't be watching that. No, no, you'll be watching... the widow Boone. Tiffany, perhaps. Oh no, better yet, "Kelli" - with an "I"!
Bebe: [tortured] Stop it!
Frasier: You'll picture her wearing YOUR jewels, sailing in YOUR yachts, sleeping with YOUR gigolos - but, oh, you won't be sad, no, no, no!
Frasier: Because you'll have your cigarette.
[Bebe stares at her cigarette with fear]
Frasier: Yeah! Clutched in your nicotine-stained teeth, smoke whirling about your once-pretty, now creased, leathery, smoke-ravaged...
Bebe: [anguished] Enough!
[Bebe hands the cigarettes to a triumphant Frasier]
Bebe: God! You are one hell of a therapist!
Frasier: Cupid and his arrow have declared me an endangered species.
Frasier: What fresh Hell awaits!
Frasier: This is Dr. Frasier Crane wishing you all good mental health.
[In some versions of the closing credits theme]
Frasier: Scrambled eggs all over my face; what is a boy to do?
Frasier: Don't stare at me, Eddie. I'm a humane man but in the mood I'm in, I could kick a kitten through an electric fan!
Frasier: You're not alone.
Agoraphobe: But I AM alone!
Frasier: Oh, fine, fine! But you're forgetting that not three days ago I was punched in the face by a man now dead!
Frasier: She's Psychic, we've decided to find it charming.
Frasier: I'm listening.
Niles: Ran up too many stairs! Lost Count! Big Dog! Need Place to Die!
Frasier: [has put his back out] All that Osteopath did was give me a bottle of Horse Tranquillisers and send me on my way! He didn't want to help me, he just wanted to shut me up!
Frasier: A Guilty Conscience Sleeps in THUNDER!
Daphne: Yum, scrum, pig's bum!
Frasier: Oh dear God!
Frasier: Oh, knock it off!
Frasier: [equating Niles' marriage with a chess game] The King is stationary while the Queen has all the power.
Niles: Nobody calls me Peach Fuzz!
Frasier: Frasier Crane has Thumped his last Melon.
Frasier: I am simply percolating with party ideas.
Frasier: [after Frasier has just met Daphne, Martin's new kooky, live-in physiotherapist] The whole idea of getting somebody in here was to help ease my burden! Not to add to it!
Martin: Oh, do you hear that, Eddie? We're a burden.
Frasier: Oh Dad! Dad, you're... you're twisting my words! I meant burden in its most positive sense!
Martin: As in, "Gee, what a lovely burden?"
Frasier: Something like that, yes!
Sam Malone: [Niles] Hey, he looks like you used to! What happened, man?
Frasier: It wasn't a Health Club you were running, there...
Frasier: You're not going to get sick. Just remember that the more you do it, the less special it will seem.
Niles: Telling you that would violate Doctor-Cat Confidentiality.
Roz: [Roz doesn't like Frasier's relationship with Julia, KACL's financial analyst] You're gonna have to choose, Frasier.
Frasier: You will not put me in this position, Roz. We will discuss it later.
Roz: No! Tell me! It's her or me! Tell me now! Or I swear to God I will walk out of here and I will not come back!