Marques Houston's reason for leaving the show was due to the fact that his mother died.

At the beginning of the show's run, a beauty mark was drawn on Tia's cheek to match the one naturally on Tamera's cheek.

For the 1994-1995 season, the show ran on the ABC Television Network. However, at the end of the second season, the network canceled the show despite consistently winning its time slot and being one of the highest rated shows on Friday nights. At that time, The WB Network just launched and picked up the show for the remainder of its run, from 1995-1999. It used to run at the 8:00 PM Sunday night time slot.

Celebrities who've made appearances throughout the program include Kenan Thompson, Kel Mitchell, Sherman Hemsley, Daphne Maxwell Reid, Kobe Bryant, Tyrese, Mary-Kate and Ashley Olsen, Lisa Leslie, Milton Berle, Boyz II Men, and Molly Shannon, and Brittney Murphy.

Richard Lawson (Victor), Lisa Landry's on-screen love romance, is real life biological father to Bianca Lawson (Rhonda Coley), the twins rival in high school and is also real life husband of Tina Knowles, singer Beyoncé's mother.

The twins' real life brother Tahj Mowry guest starred in three different episodes, each time as a different character.

The pilot was filmed in November 1993.

Other sitcoms about identical twins have included The Patty Duke Show, The Suite Life of Zack and Cody, and Double Trouble. Valerie, Full House and Desperate Housewives all also featured twin characters.