Several episodes contain plot threads that link them together. For example, the "Innobotics arc", the story of life-like androids created by the Innobotics Corporation, runs through these episodes: "Valerie 23", "Mary 25", "The Hunt", "In Our Own Image", and "Resurrection".

The Sci-Fi Channel (now Syfy) took over co-production for the seventh and final season in 2001 after the series was cancelled by Showtime.

Leonard Nimoy, David McCallum, Cliff Robertson, Barbara Rush and Peter Breck are the only actors to appear in both this series and The Outer Limits (1963).

Sam Egan, the writer of the award-winning 100th episode The Outer Limits: Tribunal (1999), based the story of the episode on his father's experience in Auschwitz during World War II, where his first wife and their young daughter were murdered by the Nazis.

The series, which ran for seven seasons, lasted considerably longer than the original version of The Outer Limits (1963), which only ran for two seasons.

One story with mostly the same original cast was shown in two parts over consecutive seasons: The Outer Limits: Double Helix (1997) and The Outer Limits: The Origin of Species (1998).

When it premiered on TV2 in New Zealand, The Outer Limits: Sandkings (1995) was the first episode of the series to be given a viewer warning at the beginning of the episode for its frightening scenes. All episodes were rated AO adults only on TV2.

Film Composer Howard Shore was hired to provide the new theme music to the series. However, when the producers heard his old fashioned orchestral theme, they decided they wanted to go with a more modern approach. John Van Tongeren heard Shore's theme and looked over it, as he was asked if he could add anything to Shore's theme. In the end, a new modern theme was done by John Van Tongeren and Mark Mancina.

Kim Coates is the only actor to appear in both the pilot and the series finale. He played Dave Stockley in The Outer Limits: Sandkings (1995) and Colonel Sage in The Outer Limits: Human Trials (2002).

An attempt to revive the series happened as far back as 1986.

Eric Schneider and Alex Diakun each appeared in eight episodes of the series, more than anyone else. Schneider is the only actor to appear in all seven seasons while Diakun appeared in all but the third. Schneider played Detective Barclay in The Outer Limits: I, Robot (1995), Dr. Golden in The Outer Limits: Vanishing Act (1996), a Triune in The Outer Limits: Feasibility Study (1997), Dr. Miles Osgoode in The Outer Limits: Fear Itself (1998), the Voice in The Outer Limits: Nightmare (1998), High Commander Reese in The Outer Limits: Summit (1999), Dr. Stanley Miller in The Outer Limits: The Gun (2000) and the Alien Interrogator in The Outer Limits: Abduction (2001). Diakun played a Minister in The Outer Limits: The Second Soul (1995), Quasga in The Outer Limits: Beyond the Veil (1996), Mr. Wilkes / Father Claridge in The Outer Limits: Fear Itself (1998), Moses Saxon in The Outer Limits: Alien Radio (1999), Nicholas Prentice in The Outer Limits: Tribunal (1999), The Outer Limits: Gettysburg (2000) and The Outer Limits: Time to Time (2001) and a shopkeeper in The Outer Limits: Alien Shop (2001).

Only fifteen actors played the same character in more than one episode: Tom Butler (Charlie Rogers, though he was called Charlie Bouton in the latter episode) and Paula Shaw (Mrs. Janus) in The Outer Limits: Valerie 23 (1995) and The Outer Limits: Mary 25 (1998), Robert Patrick (Major John Skokes) in The Outer Limits: Quality of Mercy (1995) and The Outer Limits: The Light Brigade (1996), Amanda Plummer (Dr. Theresa Givens) in The Outer Limits: A Stitch in Time (1996) and The Outer Limits: Final Appeal (2000), Jessica Harmon (Tali) and John Tench (Alex) in The Outer Limits: The Camp (1997) and The Outer Limits: Promised Land (1998), Ron Rifkin (Dr. Martin Nodel, though his first name was given as Eric in the latter episode), Ryan Reynolds (Paul Nodel), Kathleen Duborg (Hope), William deVry (Ben), Tara Spencer-Nairn (Heather), Kirby Morrow (Kirby), Silvio Pollio (Anthony) and Terri Lynn Ibisoglu (Sarah) in The Outer Limits: Double Helix (1997) and The Outer Limits: The Origin of Species (1998) and Alex Diakun (Nicholas Prentice, the only character to appear in more than two episodes) in The Outer Limits: Tribunal (1999), The Outer Limits: Gettysburg (2000) and The Outer Limits: Time to Time (2001).

Four episodes of the series were remakes of episodes of The Outer Limits (1963): The Outer Limits: I, Robot (1995) was a remake of The Outer Limits: I, Robot (1964), The Outer Limits: Feasibility Study (1997) was a remake of The Outer Limits: A Feasibility Study (1964), The Outer Limits: Nightmare (1998) was a remake of The Outer Limits: Nightmare (1963) and The Outer Limits: The Inheritors (1999) was a remake of The Outer Limits: The Inheritors: Part I (1964) and The Outer Limits: The Inheritors: Part II (1964). The Outer Limits: The Human Factor (1963) and The Outer Limits: The Human Factor (2002) have no connection beyond the title.

Two Season Seven episodes, The Outer Limits: Time to Time (2001) and The Outer Limits: Rule of Law (2001), were backdoor pilots for science fiction series which were not picked up.

Don MacKay played Dr. Charles Link in The Outer Limits: I, Robot (1995), Pat Dooley in The Outer Limits: Feasibility Study (1997) and Ollie Gibb in The Outer Limits: The Inheritors (1999). Coincidentally, all three episodes are remakes of episodes of The Outer Limits (1963). The only remake episode in which he does not appear is The Outer Limits: Nightmare (1998).

Cliff Robertson and Thora Birch were the oldest and youngest actors respectively to play the protagonist in an episode of the series: Robertson was 75 years old when he played Theodore Harris in The Outer Limits: Joyride (1999) while Birch was 12 years old when she played Aggie Travers in The Outer Limits: The Choice (1995).